Thymulin vs Gonadorelin
Side-by-side comparison of key properties, dosing, and research.
Immune Support
ThymulinSexual Health & LibidoAnti-Aging & Longevity
Gonadorelin- Summary
- Thymulin is a nonapeptide hormone produced exclusively by the thymic epithelium. It requires zinc for biological activity and plays a critical role in T-lymphocyte maturation, differentiation, and immune regulation. Thymulin levels decline dramatically with age, contributing to immunosenescence.
- Gonadorelin is the synthetic form of endogenous GnRH (gonadotropin-releasing hormone). It stimulates the pituitary to release LH and FSH, maintaining testicular function and testosterone production. Widely used alongside TRT to prevent testicular atrophy and preserve fertility.
- Half-Life
- ~30 minutes active half-life
- ~2–4 minutes (extremely short); pulsatile dosing required to avoid desensitization
- Admin Route
- SubQ
- SubQ, Intranasal
- Research
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- Typical Dose
- 20-30 mcg
- 100 mcg
- Frequency
- 10 days per month (Khavinson protocol)
- Twice daily (every 12 hours)
- Key Benefits
- Enhances T-cell maturation and differentiation
- Boosts NK cell cytotoxic activity
- Reduces inflammatory cytokine production (TNF-α, IL-1)
- Anti-nociceptive (pain-reducing) properties
- Restores age-related immune decline
- Anti-inflammatory via serotonin pathway modulation
- Maintains testicular size during TRT
- Preserves fertility and sperm production during testosterone use
- Stimulates endogenous LH/FSH production
- Maintains HPG axis function during exogenous hormone use
- Used for HCG-free TRT protocols
- Helps restart natural testosterone production (PCT)
- Side Effects
- Injection site reactions
- Mild fatigue initially as immune system activates
- Injection site reactions
- Headache
- Nausea at initiation
- Tachycardia (rare)
- +1 more
- Stacks With
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