TB-500 vs Sermorelin
Side-by-side comparison of key properties, dosing, and research.
Recovery & Repair
TB-500Growth Hormone PeptidesAnti-Aging & Longevity
Sermorelin- Summary
- TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring peptide found in nearly all human and animal cells. It promotes cell migration to injury sites, accelerates tissue regeneration, and reduces chronic inflammation.
- Sermorelin is a bioidentical synthetic peptide comprising the first 29 amino acids of naturally occurring GHRH. It is FDA-approved for diagnostic use and widely prescribed off-label for anti-aging, stimulating growth hormone production in a natural pulsatile pattern that mimics the body's own rhythm.
- Half-Life
- 2–3 hours
- 10–20 minutes
- Admin Route
- SubQ, IM
- SubQ
- Research
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- Typical Dose
- 2–2.5 mg
- 200–500 mcg
- Frequency
- Twice weekly
- 5–7 days per week
- Key Benefits
- Enhances muscle tissue regeneration
- Accelerates healing of wounds and injuries
- Reduces inflammation and pain
- Improves flexibility and mobility
- Promotes new blood vessel formation
- Supports hair growth and skin health
- May improve cardiac function after injury
- Systemic healing effect — works at distance from injection site
- Increases energy and vitality
- Improves body composition (more muscle, less fat)
- Enhances skin thickness and elasticity
- Strengthens immune system
- Improves sleep quality and REM sleep
- Supports bone density
- Enhances mental clarity and focus
- Safer than exogenous HGH — respects natural feedback loops
- FDA-approved for GH diagnostic use
- Side Effects
- Injection site discomfort
- Fatigue (rare)
- Headache (rare)
- Injection site irritation
- Flushing
- Headache
- Dizziness
- +2 more
- Stacks With
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