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ToolsCompareEnclomiphene vs Vilon

Enclomiphene vs Vilon

Side-by-side comparison of key properties, dosing, and research.

GLP-1 / Weight Loss Agonists
Enclomiphene
Immune SupportAnti-Aging & Longevity
Vilon
Summary
Enclomiphene is the trans-isomer of clomiphene citrate, a selective estrogen receptor modulator (SERM) that stimulates endogenous testosterone production by blocking estrogen negative feedback on the hypothalamus and pituitary. Unlike TRT, it restores testosterone while preserving or increasing sperm production and testicular volume.
Vilon is a synthetic dipeptide (Lys-Glu) derived from the thymus gland extract Thymalin. The shortest immune-regulatory peptide known, Vilon modulates T-cell and NK-cell function, extends lifespan in animal models, and shows epigenetic anti-aging activity. It is one of the Khavinson peptide bioregulators.
Half-Life
5-7 days (long half-life; accumulates)
Very short as a free dipeptide; effects mediated via gene regulation
Admin Route
Oral
SubQ, Oral
Research
Typical Dose
12.5-25 mg per day
1–2 mg SC daily or 5–10 mg oral daily
Frequency
Once daily or every other day
Once daily
Key Benefits
  • Restores testosterone to normal range without exogenous androgen administration
  • Preserves or increases sperm production and fertility
  • Maintains testicular volume (unlike TRT which causes testicular atrophy)
  • LH and FSH levels rise, indicating intact HPG axis function
  • Option for hypogonadal men desiring fertility
  • Oral administration (no injection required)
  • Immune system modulation and restoration
  • Lifespan extension (30–40% in animal studies)
  • T-cell and NK-cell activation
  • Epigenetic anti-aging activity
  • Reduces oxidative stress markers
  • Antioxidant gene upregulation
  • May prevent age-related immune senescence
  • Anti-tumor immune surveillance
Side Effects
  • Visual disturbances (rare but class-related SERM effect)
  • Mood changes or irritability
  • Hot flashes
  • Elevated estradiol in some users
  • +2 more
  • Excellent safety profile, decades of Russian clinical use
  • Rare: mild injection site reaction
  • Very rare: mild allergic reaction
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