New — Free Peptide Starter Guide (2026): 13 chapters, 34 cited studies

Get it free
ToolsCompareEnclomiphene vs GHRP-2

Enclomiphene vs GHRP-2

Side-by-side comparison of key properties, dosing, and research.

GLP-1 / Weight Loss Agonists
Enclomiphene
Growth Hormone Peptides
GHRP-2
Summary
Enclomiphene is the trans-isomer of clomiphene citrate, a selective estrogen receptor modulator (SERM) that stimulates endogenous testosterone production by blocking estrogen negative feedback on the hypothalamus and pituitary. Unlike TRT, it restores testosterone while preserving or increasing sperm production and testicular volume.
GHRP-2 is a potent synthetic hexapeptide that stimulates growth hormone release by activating ghrelin receptors in the pituitary and hypothalamus. It produces one of the strongest GH pulses among GHRPs, though unlike Ipamorelin it does cause modest increases in cortisol and prolactin.
Half-Life
5-7 days (long half-life; accumulates)
15–60 minutes
Admin Route
Oral
SubQ, Intranasal
Research
Typical Dose
12.5-25 mg per day
100–300 mcg
Frequency
Once daily or every other day
2–3 times daily
Key Benefits
  • Restores testosterone to normal range without exogenous androgen administration
  • Preserves or increases sperm production and fertility
  • Maintains testicular volume (unlike TRT which causes testicular atrophy)
  • LH and FSH levels rise, indicating intact HPG axis function
  • Option for hypogonadal men desiring fertility
  • Oral administration (no injection required)
  • Strong GH pulse stimulation
  • Increased IGF-1 levels
  • Enhanced muscle growth and recovery
  • Improved fat metabolism
  • Better sleep quality
  • Increased bone density
  • Enhanced appetite (less pronounced than GHRP-6)
  • Anti-aging effects via GH axis optimization
Side Effects
  • Visual disturbances (rare but class-related SERM effect)
  • Mood changes or irritability
  • Hot flashes
  • Elevated estradiol in some users
  • +2 more
  • Increased appetite
  • Water retention
  • Elevated cortisol (modest)
  • Elevated prolactin (modest)
  • +2 more
Stacks With