CJC-1295 vs Gonadorelin
Side-by-side comparison of key properties, dosing, and research.
Growth Hormone Peptides
CJC-1295Sexual Health & LibidoAnti-Aging & Longevity
Gonadorelin- Summary
- CJC-1295 is a synthetic GHRH analog that stimulates the pituitary gland to produce and release growth hormone. The DAC (Drug Affinity Complex) version has a markedly extended half-life. The No DAC version (Modified GRF 1-29) preserves natural pulsatile GH release and is preferred in most protocols.
- Gonadorelin is the synthetic form of endogenous GnRH (gonadotropin-releasing hormone). It stimulates the pituitary to release LH and FSH, maintaining testicular function and testosterone production. Widely used alongside TRT to prevent testicular atrophy and preserve fertility.
- Half-Life
- ~30 minutes (No DAC) / 6–8 days (with DAC)
- ~2–4 minutes (extremely short); pulsatile dosing required to avoid desensitization
- Admin Route
- SubQ
- SubQ, Intranasal
- Research
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- Typical Dose
- 100 mcg
- 100 mcg
- Frequency
- Once daily, before bed
- Twice daily (every 12 hours)
- Key Benefits
- Sustained increase in growth hormone levels
- Enhanced muscle growth and strength
- Improved fat metabolism and body composition
- Better recovery and tissue repair
- Increased bone density
- Enhanced immune function
- Improved skin quality and collagen production
- Synergistic GH release when combined with GHRPs like Ipamorelin
- Maintains testicular size during TRT
- Preserves fertility and sperm production during testosterone use
- Stimulates endogenous LH/FSH production
- Maintains HPG axis function during exogenous hormone use
- Used for HCG-free TRT protocols
- Helps restart natural testosterone production (PCT)
- Side Effects
- Water retention / puffiness
- Carpal tunnel syndrome (with prolonged use)
- Injection site irritation
- Hunger increase (minor)
- +1 more
- Injection site reactions
- Headache
- Nausea at initiation
- Tachycardia (rare)
- +1 more
- Stacks With
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