New — Free Peptide Starter Guide (2026): 13 chapters, 34 cited studies

Get it free
ToolsCompareAOD-9604 vs Triptorelin

AOD-9604 vs Triptorelin

Side-by-side comparison of key properties, dosing, and research.

Fat Loss & Metabolic
AOD-9604
Sexual Health & Libido
Triptorelin
Summary
AOD-9604 is a modified fragment of human growth hormone (residues 177-191) with an additional tyrosine residue that significantly enhances bioavailability. Originally developed as an anti-obesity drug by Metabolic Pharmaceuticals, it stimulates lipolysis and inhibits lipogenesis without the diabetogenic effects of full GH.
Triptorelin is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH) with 100x the potency of native GnRH. An FDA-approved drug (Trelstar) for prostate cancer and precocious puberty, it is also used in post-cycle therapy (PCT) to rapidly restart the hypothalamic-pituitary-gonadal (HPG) axis after anabolic steroid suppression.
Half-Life
30-45 minutes injectable; longer with nasal spray formulation
Depot forms: weeks to months; aqueous: 6-8 hours
Admin Route
SubQ, Intranasal, Oral
SubQ, IM
Research
Typical Dose
300-600 mcg
100 mcg
Frequency
Once daily
Single injection
Key Benefits
  • Selective fat loss without anabolic side effects
  • No effect on blood glucose or insulin resistance
  • Improved bioavailability over Fragment 176-191
  • GRAS (Generally Recognized As Safe) status in Australia
  • Potential cartilage repair and anti-inflammatory properties
  • Does not suppress natural GH production
  • Rapid HPG axis restart after steroid use
  • Single-injection PCT protocol possible
  • Massively elevates LH and FSH via flare effect
  • Restores endogenous testosterone faster than traditional PCT
  • FDA-approved for established medical uses
Side Effects
  • Localized injection site reactions
  • Headache (rare)
  • Hypoglycemia risk in combination with insulin (very rare)
  • Initial testosterone flare (intended)
  • Injection site reactions
  • Hot flashes (with chronic use)
  • Decreased libido (chronic dosing)
Stacks With