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Prostamax

Also known as: Lys-Glu-Asp-Pro, Khavinson prostate peptide, Prostatic bioregulator

Prostamax is a tetrapeptide bioregulator (Lys-Glu-Asp-Pro) developed by Professor Vladimir Khavinson, tissue-specific for the prostate gland. It supports prostate epithelial cell function, promotes normalization of prostate tissue, and is studied for its potential in benign prostatic hyperplasia (BPH), prostatitis, and prostate anti-aging. It is one of the more widely used Khavinson bioregulators among men over 40.

Half-Life

Short (minutes); sustained gene-regulatory effects

Route

SubQ, Oral

Category

Anti-Aging & Longevity

Studies

3 references

Key Benefits

  • Supports normalization of prostate tissue architecture
  • May reduce prostate enlargement associated with BPH
  • Anti-inflammatory effects on prostatic tissue
  • Reduces prostate cell apoptosis from oxidative stress
  • Potential support in chronic prostatitis
  • Anti-aging effects on prostate glandular tissue
  • Complementary to conventional BPH therapies

Mechanism of Action

Prostamax acts as a gene expression modulator in prostate epithelial and stromal cells. The tetrapeptide Lys-Glu-Asp-Pro interacts with chromatin in prostate tissue, normalizing protein synthesis, reducing abnormal cellular proliferation associated with BPH, and supporting healthy glandular architecture. It reduces inflammatory cytokine expression in prostate tissue and may inhibit excessive androgen receptor signaling contributing to prostatic enlargement.

Dosing Protocols

Standard Khavinson Protocol

Dose
10 mg per day
Frequency
Daily for 10–30 days
Timing
Subcutaneous injection or oral (enteric-coated)
Cycle
10–30 day course, repeated 2–4x per year

Often combined with Testagen in men's health protocols. Research use only.

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Side Effects

  • Generally well tolerated in available research
  • Mild injection site reactions
  • No significant adverse urological events reported at standard doses

Contraindications

Not FDA approved. Not a substitute for alpha-blockers, 5-alpha reductase inhibitors, or other BPH treatments. Medical oversight required for prostate conditions or elevated PSA.

Storage

Store at 2–8°C. Protect from moisture and light.

  1. 1.
    Peptides (Epigenetic Regulators) in the Structure of Rodents with a Long and Short Lifespan

    Khavinson VK, Kormilets DY, Mar'yanovich AT · Bulletin of experimental biology and medicine · 2017PubMed Verified

  2. 2.
    Microcalorimetric study of human blood lymphocytes culture at presence of copper, cadmium and prostamax

    Kiladze M, Gorgoshidze M, Monaselidze J, Jokhadze T, Lezhava T · Georgian medical news · 2009PubMed Verified

  3. 3.
    Effects of short peptides on lymphocyte chromatin in senile subjects

    Khavinson VKh, Lezhava TA, Malinin VV · Bulletin of experimental biology and medicine · 2004PubMed Verified

Medical disclaimer: This information is for educational purposes only and does not constitute medical advice. Many compounds listed are research chemicals not approved for human use. Always consult a qualified healthcare professional before starting any protocol.

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