Thymalin vs Thymosin Alpha-1
Side-by-side comparison of key properties, dosing, and research.
Immune SupportAnti-Aging & Longevity
ThymalinImmune SupportAnti-Aging & Longevity
Thymosin Alpha-1- Summary
- Thymalin is a polypeptide complex isolated from calf thymus glands (developed by the Russian Gerontology Institute), shown to restore immune function, extend lifespan, and reverse thymic involution. Clinical studies demonstrate improved immune parameters and up to 40% reduction in mortality in elderly patients.
- Thymosin Alpha-1 is a naturally occurring 28-amino acid peptide derived from the thymus gland. It is a powerful immune modulator approved in many countries for treating chronic hepatitis B, hepatitis C, and as an adjunct in cancer immunotherapy.
- Half-Life
- Not well characterized as a complex extract; individual peptides have varying kinetics
- 2–3 hours
- Admin Route
- SubQ, IM
- SubQ
- Research
- —
- —
- Typical Dose
- 10 mg IM or SC daily
- 0.8–1.6 mg
- Frequency
- Once daily
- Twice weekly
- Key Benefits
- Restores thymic function and T-cell immunity
- Extends healthy lifespan (documented in long-term studies)
- Reduces infectious disease incidence in elderly
- Normalizes immune parameters in immunodeficiency
- Anti-tumor immune surveillance
- Improves vaccine response in elderly
- Reduces cardiovascular mortality (40% in landmark Russian study)
- Normalizes neuroendocrine function
- Enhances T-cell and NK cell activity
- Supports recovery from viral and bacterial infections
- May reduce inflammation systemically
- Supports healthy aging and immune resilience
- Improves vaccine response
- Supports liver health
- May help with chronic fatigue syndrome and post-viral conditions
- Approved in multiple countries for hepatitis B and C treatment
- Side Effects
- Very well tolerated in decades of Russian clinical use
- Mild injection site reactions
- Rare: mild allergic reaction (natural extract)
- Transient flu-like symptoms on initiation (immune activation)
- Injection site irritation
- Mild flu-like symptoms initially (immune activation)
- Fatigue (rare)
- Stacks With
- —
- —