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ToolsCompareTB-500 vs Follistatin 344

TB-500 vs Follistatin 344

Side-by-side comparison of key properties, dosing, and research.

Recovery & Repair
TB-500
Anabolic & IGF
Follistatin 344
Summary
TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring peptide found in nearly all human and animal cells. It promotes cell migration to injury sites, accelerates tissue regeneration, and reduces chronic inflammation.
Follistatin 344 is a recombinant form of the endogenous follistatin protein. It inhibits myostatin and activin — the primary negative regulators of muscle growth — potentially removing the genetic ceiling on muscle development. It is one of the most theoretically powerful anabolic compounds but is experimental with limited human data.
Half-Life
2–3 hours
~24–36 hours
Admin Route
SubQ, IM
SubQ, IM
Research
Typical Dose
2–2.5 mg
100 mcg
Frequency
Twice weekly
Once daily
Key Benefits
  • Enhances muscle tissue regeneration
  • Accelerates healing of wounds and injuries
  • Reduces inflammation and pain
  • Improves flexibility and mobility
  • Promotes new blood vessel formation
  • Supports hair growth and skin health
  • May improve cardiac function after injury
  • Systemic healing effect — works at distance from injection site
  • Inhibits myostatin — removes muscle growth ceiling
  • Significant increases in muscle mass and strength
  • Reduces fat mass
  • Promotes bone density
  • May stimulate hair follicle cycling
  • Anti-fibrotic effects in muscle tissue
  • Synergistic with IGF-1 and other anabolic peptides
Side Effects
  • Injection site discomfort
  • Fatigue (rare)
  • Headache (rare)
  • Muscle soreness (from rapid hypertrophy)
  • Potential reproductive effects (activin inhibition)
  • Unknown long-term safety profile
  • Possible esophageal effects at high doses (animal data)
Stacks With