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ToolsCompareMelanotan II vs Vilon

Melanotan II vs Vilon

Side-by-side comparison of key properties, dosing, and research.

Sexual Health & Libido
Melanotan II
Immune SupportAnti-Aging & Longevity
Vilon
Summary
Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that stimulates melanin production (skin tanning), suppresses appetite, and enhances sexual function. It is not FDA-approved and has significant safety concerns including mole changes and cardiovascular effects.
Vilon is a synthetic dipeptide (Lys-Glu) derived from the thymus gland extract Thymalin. The shortest immune-regulatory peptide known, Vilon modulates T-cell and NK-cell function, extends lifespan in animal models, and shows epigenetic anti-aging activity. It is one of the Khavinson peptide bioregulators.
Half-Life
1–2 hours
Very short as a free dipeptide; effects mediated via gene regulation
Admin Route
SubQ
SubQ, Oral
Research
Typical Dose
0.25–0.5 mg
1–2 mg SC daily or 5–10 mg oral daily
Frequency
Once daily
Once daily
Key Benefits
  • Promotes skin tanning and melanin production
  • Reduces UV exposure needed to tan
  • Enhances libido and sexual function
  • May suppress appetite
  • Faster, deeper tan development
  • Longer-lasting tan maintenance
  • Potential photoprotective effects
  • Immune system modulation and restoration
  • Lifespan extension (30–40% in animal studies)
  • T-cell and NK-cell activation
  • Epigenetic anti-aging activity
  • Reduces oxidative stress markers
  • Antioxidant gene upregulation
  • May prevent age-related immune senescence
  • Anti-tumor immune surveillance
Side Effects
  • Nausea (very common, especially in first days)
  • Facial flushing
  • Spontaneous erections in men
  • Darkening or changes in existing moles (monitor closely)
  • +3 more
  • Excellent safety profile, decades of Russian clinical use
  • Rare: mild injection site reaction
  • Very rare: mild allergic reaction
Stacks With