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ToolsCompareMelanotan II vs GHRP-2

Melanotan II vs GHRP-2

Side-by-side comparison of key properties, dosing, and research.

Sexual Health & Libido
Melanotan II
Growth Hormone Peptides
GHRP-2
Summary
Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that stimulates melanin production (skin tanning), suppresses appetite, and enhances sexual function. It is not FDA-approved and has significant safety concerns including mole changes and cardiovascular effects.
GHRP-2 is a potent synthetic hexapeptide that stimulates growth hormone release by activating ghrelin receptors in the pituitary and hypothalamus. It produces one of the strongest GH pulses among GHRPs, though unlike Ipamorelin it does cause modest increases in cortisol and prolactin.
Half-Life
1–2 hours
15–60 minutes
Admin Route
SubQ
SubQ, Intranasal
Research
Typical Dose
0.25–0.5 mg
100–300 mcg
Frequency
Once daily
2–3 times daily
Key Benefits
  • Promotes skin tanning and melanin production
  • Reduces UV exposure needed to tan
  • Enhances libido and sexual function
  • May suppress appetite
  • Faster, deeper tan development
  • Longer-lasting tan maintenance
  • Potential photoprotective effects
  • Strong GH pulse stimulation
  • Increased IGF-1 levels
  • Enhanced muscle growth and recovery
  • Improved fat metabolism
  • Better sleep quality
  • Increased bone density
  • Enhanced appetite (less pronounced than GHRP-6)
  • Anti-aging effects via GH axis optimization
Side Effects
  • Nausea (very common, especially in first days)
  • Facial flushing
  • Spontaneous erections in men
  • Darkening or changes in existing moles (monitor closely)
  • +3 more
  • Increased appetite
  • Water retention
  • Elevated cortisol (modest)
  • Elevated prolactin (modest)
  • +2 more
Stacks With