New — Free Peptide Starter Guide (2026): 13 chapters, 34 cited studies

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Protocol Category

Immune Support

Thymic and antimicrobial peptide protocols for immune modulation and resilience.

Beginner

Intermediate

Intermediate4 compounds

Alopecia Areata & Autoimmune Hair Loss Protocol

A targeted protocol for alopecia areata (autoimmune hair loss) combining immune-modulating peptides with hair follicle growth stimulants to address both the inflammatory root cause and promote follicular re-activation.

Intermediate4 compounds

Ankylosing Spondylitis & Axial Spondyloarthropathy Protocol

A peptide-based adjunct protocol for ankylosing spondylitis (AS) and axial spondyloarthropathy (axSpA), targeting the IL-17A/TNF-driven inflammation, spinal ligament ossification cascade, and associated gut microbiome dysbiosis.

Intermediate5 compounds

Autoimmune & Systemic Inflammation Protocol

A comprehensive protocol targeting autoimmune dysregulation and chronic systemic inflammation using peptides that modulate immune checkpoints, reduce cytokine storms, and restore peripheral tolerance.

Intermediate6 compounds

Celiac Disease & Gluten-Related Disorders Protocol

An adjunctive protocol for individuals with celiac disease or non-celiac gluten sensitivity, targeting the intestinal barrier dysfunction, autoimmune mucosal damage, and nutritional malabsorption that persist despite gluten-free diet adherence.

Intermediate5 compounds

Chronic Fatigue & Post-Viral Recovery Protocol

Targeted protocol for chronic fatigue syndrome, post-viral fatigue (including long COVID), and ME/CFS. Addresses mitochondrial dysfunction, immune dysregulation, and neuroinflammation simultaneously.

Intermediate5 compounds

Chronic Lyme Disease & Post-Lyme Syndrome Protocol

A comprehensive immune-restoration and symptom-management protocol for chronic Lyme disease and post-treatment Lyme disease syndrome (PTLDS), addressing persistent inflammation, neuropathic pain, and immune dysregulation.

Intermediate4 compounds

Endometriosis & Pelvic Pain Management Protocol

A peptide-based adjunct protocol for endometriosis addressing the chronic pelvic inflammatory environment, adhesion formation, neuro-sensitization underlying dysmenorrhea, and the immune dysregulation driving retrograde endometrial implantation.

Intermediate4 compounds

Immune Defense & Longevity Protocol

A comprehensive immune optimization stack combining a clinically-approved immune modulator, thymus restoration, antimicrobial defense, and anti-inflammatory peptides to build robust immune resilience, especially valuable for chronic infections, post-viral recovery, and immune aging.

Intermediate5 compounds

Immune Restoration & Anti-Inflammatory Protocol

A comprehensive immune system restoration and chronic inflammation reduction protocol targeting multiple immune pathways. Addresses T-cell function, NK cell activity, regulatory immune balance, and systemic inflammatory cytokine reduction.

Intermediate4 compounds

Inflammatory Bowel Disease (Crohn's & Ulcerative Colitis)

A gut-targeted peptide protocol for Crohn's disease and ulcerative colitis, addressing mucosal barrier restoration, Th17/Treg immune dysregulation, microbiome normalization, and reduction of inflammatory cytokine cascade in remission maintenance.

Intermediate5 compounds

Long COVID & Post-Viral Fatigue Recovery Protocol

A comprehensive immune restoration and mitochondrial recovery protocol for Long COVID and post-viral fatigue syndrome, addressing persistent viral immune dysregulation, autonomic dysfunction, and cellular energy failure.

Intermediate6 compounds

Psoriasis & Inflammatory Skin Conditions Protocol

A peptide protocol for individuals with psoriasis, psoriatic arthritis, or chronic inflammatory skin conditions. Targets the dysregulated Th17/IL-23 axis, keratinocyte hyperproliferation, skin barrier dysfunction, and gut-skin axis immune dysregulation that drive psoriatic disease.

Intermediate5 compounds

Psoriasis & Inflammatory Skin Disease Protocol

A peptide protocol combining systemic anti-inflammatory, immunomodulatory, and barrier-repair compounds to manage psoriasis plaques, reduce flare frequency, and restore skin barrier integrity.

Intermediate4 compounds

Psoriasis & Psoriatic Arthritis Management Protocol

A peptide-based adjunct protocol for psoriasis and psoriatic arthritis, targeting the IL-23/Th17 axis, skin barrier dysfunction, and inflammatory arthropathy that characterize psoriatic disease.

Intermediate5 compounds

Rheumatoid Arthritis & Autoimmune Joint Disease Protocol

A targeted protocol for rheumatoid arthritis and autoimmune joint conditions combining immunomodulation, synovial inflammation reduction, cartilage protection, and joint tissue repair.

Intermediate4 compounds

Rheumatoid Arthritis Joint & Immune Protocol

A peptide-based adjunct protocol for rheumatoid arthritis (RA) targeting synovial inflammation, joint destruction prevention, immune dysregulation, and the systemic cardiovascular and metabolic comorbidities of active RA.

Intermediate4 compounds

Skin Cancer Prevention & UV Defense Protocol

A protective protocol for high UV-exposure individuals combining systemic melanin upregulation, DNA repair enhancement, immunosurveillance optimization, and skin barrier protection to reduce UV-induced carcinogenesis risk.

Advanced

Advanced6 compounds

Ankylosing Spondylitis & Axial Spondyloarthropathy Protocol

An adjunctive protocol for individuals with ankylosing spondylitis and axial spondyloarthropathy, targeting the IL-17/IL-23-driven enthesitis, progressive syndesmophyte formation, and the TNF-driven inflammatory cascade that cause irreversible spinal fusion.

Advanced4 compounds

Ankylosing Spondylitis & Axial Spondyloarthropathy Protocol

Anti-inflammatory and joint-protective peptide protocol for ankylosing spondylitis targeting spinal inflammation, syndesmophyte prevention, and preservation of spinal mobility.

Advanced5 compounds

Crohn's Disease & IBD Management Protocol

Peptide-based protocol targeting intestinal inflammation, barrier repair, and mucosal immune regulation for Crohn's disease and ulcerative colitis management.

Advanced4 compounds

Endometriosis & Pelvic Pain Management Protocol

Multi-mechanism peptide protocol for endometriosis addressing peritoneal inflammation, lesion-driven angiogenesis, central sensitization pain, and immune dysregulation underlying the disease.

Advanced6 compounds

HIV Support & Immune Restoration Protocol

A supportive protocol for people living with HIV on stable antiretroviral therapy (ART), addressing residual immune activation, HIV-associated neurocognitive disorders (HAND), peripheral neuropathy, lean mass wasting, and accelerated aging phenotypes.

Advanced4 compounds

Hashimoto's Thyroiditis & Autoimmune Thyroid Protocol

Immunomodulatory peptide protocol targeting the autoimmune destruction of thyroid tissue in Hashimoto's, aimed at reducing TPO/TG antibody titers, restoring immune tolerance, and protecting residual thyroid function.

Advanced6 compounds

Hashimoto's Thyroiditis & Autoimmune Thyroid Protocol

An adjunctive protocol for individuals with Hashimoto's thyroiditis targeting the Th1/Th17 dysregulation, molecular mimicry mechanisms, and intestinal barrier dysfunction that drive thyroid autoantibody production and progressive thyroid destruction.

Advanced6 compounds

Hepatitis C & Viral Hepatitis Support Protocol

A supportive protocol for patients with chronic viral hepatitis (HCV, HBV) combining thymic immune restoration, direct antiviral peptides, and hepatoprotective compounds to enhance viral clearance, reduce hepatic fibrosis, and improve treatment outcomes alongside standard antiviral therapy.

Advanced6 compounds

Inflammatory Bowel Disease (Crohn's) Management Protocol

An adjunctive protocol targeting the intestinal barrier dysfunction, mucosal inflammation, and immune dysregulation central to Crohn's disease and severe ulcerative colitis, designed to complement but not replace conventional IBD therapy.

Advanced4 compounds

Lupus (SLE) Immune Modulation Protocol

A peptide-based adjunct protocol for systemic lupus erythematosus (SLE), targeting the type I interferon excess, Th17/Treg imbalance, and autoantibody-driven tissue inflammation underlying lupus flares.

Advanced4 compounds

Lupus (SLE) Immune Regulation Protocol

Targeted immunomodulatory peptide protocol for systemic lupus erythematosus (SLE) aimed at restoring immune tolerance, reducing autoantibody production, and protecting target organs.

Advanced5 compounds

Mold Illness & CIRS Recovery Protocol

A multi-target protocol for Chronic Inflammatory Response Syndrome (CIRS) from mold biotoxin exposure, addressing immune dysregulation, neuroinflammation, VIP deficiency, and mucosal healing.

Advanced6 compounds

Multiple Sclerosis Immune Modulation Protocol

A peptide protocol for individuals with relapsing-remitting or progressive multiple sclerosis seeking complementary immune modulation and neuroprotection. Targets the dysregulated Th1/Th17 autoimmune response, demyelination, neuroinflammation, and axonal loss that drive MS progression.

Advanced6 compounds

Multiple Sclerosis Neuroprotection & Remyelination Protocol

A neuroprotective and pro-remyelination protocol for multiple sclerosis targeting neuroinflammation suppression, oligodendrocyte progenitor activation, axonal protection, and immune tolerance restoration.

Advanced5 compounds

Multiple Sclerosis Neuroprotective Support Protocol

A multi-target adjunct protocol for multiple sclerosis addressing T-cell mediated autoimmunity, demyelination, neuropathic pain, mitochondrial failure in neurons, and gastrointestinal health.

Advanced5 compounds

Post-Chemotherapy Recovery & Immune Reconstitution

A comprehensive peptide recovery protocol for cancer survivors completing chemotherapy, targeting immune system reconstitution, GI mucosal repair, peripheral neuropathy recovery, fatigue reduction, and restoration of hematopoietic function.

Advanced6 compounds

Post-Chemotherapy Recovery & Immune Reconstitution Protocol

A comprehensive recovery protocol for cancer survivors completing chemotherapy, addressing the profound immune depletion, peripheral neuropathy, mitochondrial toxicity, gut mucosal damage, and persistent fatigue that characterize post-chemotherapy syndrome.

Advanced6 compounds

Post-Organ Transplant Support Protocol

A supportive peptide protocol for organ transplant recipients to reduce rejection risk, support tissue integration, minimize immunosuppressant toxicity, and promote organ function recovery. All interventions must be reviewed with the transplant team, as this is a medically complex population.

Advanced5 compounds

Post-Transplant Longevity & Infection Resistance Protocol

An immunomodulatory and anti-aging adjunct protocol for organ transplant recipients aiming to preserve graft function, combat the accelerated aging driven by immunosuppression, and reduce infection risk.

Advanced6 compounds

Rheumatoid Arthritis & Autoimmune Joint Disease Management Protocol

An adjunctive protocol for individuals with rheumatoid arthritis or other autoimmune joint conditions, targeting the T-cell dysregulation, inflammatory signaling cascades, and joint tissue destruction characteristic of autoimmune arthropathies.

Advanced5 compounds

Scleroderma & Systemic Sclerosis Protocol

A multi-target protocol for scleroderma (systemic sclerosis) addressing the three core pathological processes: autoimmune activation, vasculopathy, and progressive fibrosis.

Advanced6 compounds

Sepsis Recovery & Systemic Inflammation Resolution Protocol

A targeted protocol for post-sepsis syndrome recovery, addressing the persistent immunosuppression, organ damage, and hyperinflammatory sequelae that follow septic episodes.

Advanced6 compounds

Systemic Lupus Erythematosus (SLE) Management Protocol

An adjunctive protocol for individuals with SLE targeting the pathological T-cell and B-cell dysregulation, complement overactivation, end-organ inflammation, and accelerated aging processes that characterize this complex systemic autoimmune disease.

Advanced5 compounds

Thymic Immune Bioregulator Stack

Comprehensive thymic restoration stack using short-chain bioregulatory peptides from the thymus gland to reverse immunosenescence, restore T-cell diversity, and rebuild adaptive immunity in aging individuals.

Advanced5 compounds

Thymic Immune Restoration Protocol

Full thymic axis restoration protocol for immunosenescence reversal, T-cell diversity expansion, and enhanced immune surveillance. Combines thymic peptides, antimicrobial defense, and NAD+ immune energetics.

Advanced5 compounds

Type 1 Diabetes Immune Modulation & Beta-Cell Preservation Protocol

A protocol targeting the autoimmune mechanisms of Type 1 diabetes to preserve remaining beta-cell mass, reduce islet inflammation, restore immune tolerance to beta-cell antigens, and improve glycemic control.

Advanced4 compounds

Type 1 Diabetes Immune Modulation & Beta-Cell Support

A peptide-based adjunct protocol for Type 1 diabetes and LADA (Latent Autoimmune Diabetes in Adults) targeting beta-cell preservation, autoimmune tolerance restoration, and reduction of the accelerating autoimmune destruction that characterizes newly-diagnosed and early T1D.